MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a 16-residue peptide whose coding sequence sits within mitochondrial DNA. It is one of a small group of mitochondria-derived peptides studied as signaling molecules.
In published cell-culture work, MOTS-c has been examined in AMPK phosphorylation assays, folate-cycle and purine-biosynthesis metabolite profiling, and nuclear translocation imaging under cell-stress conditions.
Specifications
- Sequence: MRWQEMGYIFYPRKLR (16 residues)
- Quantity: 40mg per vial (net peptide content 41.22 mg)
- Form: lyophilized powder
- Purity: 99.78% (HPLC)
- Identity: confirmed (HPLC retention-time match)
- Endotoxin (USP <85>): 0.08 EU/mL
- Heavy metals (ICP-MS): not detected
- Lot: MOTS40-RD-4754 · ILS Laboratories COA-2026-I_SDFN, analyzed 07/07/2026 (see COAs tab)
Storage: Store lyophilized material at −20 °C, protected from light and moisture.
For in vitro laboratory research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or dietary supplement. Not for diagnostic or therapeutic use.
For in vitro laboratory research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or dietary supplement. Not for diagnostic or therapeutic use.